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Symbol Name ID |
Fcgr4
Fc receptor, IgG, low affinity IV MGI:2179523 |
| Darker colors indicate more annotations |
| Human Phenotypes | Reduced natural killer cell activity |
Monoclonal immunoglobulin M proteinemia |
Polyclonal elevation of IgM |
Abnormal bleeding |
Epistaxis |
Gingival bleeding |
Gastrointestinal hemorrhage |
Retinal hemorrhage |
Purpura |
Hemolytic anemia |
Normocytic anemia |
Leukopenia |
Reduced natural killer cell count |
Impaired lymphocyte transformation with phytohemagglutinin |
Abnormality of neutrophils |
Hemophagocytosis |
Leukemia |
Arterial thrombosis |
Superficial thrombophlebitis |
Hypercoagulability |
Abnormality of thrombocytes |
Thrombocytopenia |
Lymphoma |
Myelodysplasia |
Elevated erythrocyte sedimentation rate |
Splenomegaly |
Hepatosplenomegaly |
| Disease(s) Associated with FCGR3A | |||||||||||||||||||||||||||
| autoimmune thrombocytopenic purpura | |||||||||||||||||||||||||||
| Behcet's disease | |||||||||||||||||||||||||||
| graft-versus-host disease | |||||||||||||||||||||||||||
| IgA glomerulonephritis | |||||||||||||||||||||||||||
| immunodeficiency 20 | |||||||||||||||||||||||||||
| lymphoplasmacytic lymphoma | |||||||||||||||||||||||||||
| myelodysplastic syndrome | |||||||||||||||||||||||||||
| rheumatoid arthritis | |||||||||||||||||||||||||||
| systemic lupus erythematosus | |||||||||||||||||||||||||||
| temporal arteritis |
| Mouse Phenotypes | decreased osteoclast cell number |
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| Availability | Mouse Genotype | |
| Fcgr4tm1Rav/Fcgr4tm1Rav Tg(Ctsk-cre)1Rda/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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